Download Advances in Chromatography, Volume 47 by Eli Grushka, Nelu Grinberg PDF

By Eli Grushka, Nelu Grinberg

For greater than 4 many years, scientists and researchers have relied upon the Advances in Chromatography sequence for the main updated info on a variety of advancements in chromatographic tools and functions. protecting the state-of-the-art in separation technological know-how, this quantity keeps to offer well timed, state-of-the-art reports on chromatography within the fields of bio-, analytical, natural, polymer, and pharmaceutical chemistry. Compiled by means of top researchers from worldwide, new chapters conceal themes with regards to countercurrent chromatography and large-scale genotyping in addition to cyclic voltammetry detection, a robust instrument for deciding upon the electrochemical features of natural compounds.

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New Drug Approvals (series), Washington, DC: PhRMA. 2. Pharmaceutical Research and Manufacturers of America. 2001–2003. New Drugs in Development (series), Washington, DC: PhRMA. 3. Kola, I. and Landis, J. 2004. Can the pharmaceutical industry reduce attrition rates? Nat. Rev. Drug Discov. 3: 711–716. 4. Mullin, R. 2003. 7 billion. Chem. Eng. News 81: 8–9. 5. Pramanik, B. , Bartner, P. , and Chen, G. 1999. The role of mass spectrometry in the drug discovery process. Curr. Opin. Drug Discov. Devel.

Chem. 79: 3830–3842. 62. Cohen, P. 2000. The regulation of protein function by multisite phosphorylation— a 25 year update. Trends Biochem. Sci. 25: 596–601. 63. Graves, J. D. and Krebs, E. D. 1999. Protein phosphorylation and signal transduction. Pharmacol. Ther. 82: 111–121. 64. Blume-Jensen, P. and Hunter, T. 2001. Oncogenic kinase signaling. Nature 411: 355–365. 65. Cohen, P. 2002. Timeline: Protein kinases—the major drug targets of the twenty-first century? Nat. Rev. Drug Discov. 1: 309–315.

Vestal, M. L. and Campbell, J. M. 2005. Tandem time-of-flight mass spectrometry. Methods Enzymol. 402: 79–108. 16. Chernushevich, I. , Loboda, A. , and Thomson, B. A. 2001. An introduction to quadrupole-time-of-flight mass spectrometry. J. Mass Spectrom. 36: 849–865. 17. , Noll, R. , and Cooks, R. G. 2005. The orbitrap: A new mass spectrometer. J. Mass Spectrom. 40: 430–443. 18. , and Horning, S. 2006. Performance evaluation of a hybrid linear ion trap/orbitrap mass spectrometer. Anal. Chem. 78: 2113–2120.

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